From the archive: In this report from Aug. 15, 2008, "48 Hours" investigates the case of the American student who was jailed in Italy for her roommate's murder. Correspondent Peter Van Sant reports.

True crime. Real justice. To miss it would be a crime.

Devastated after the FBI bows out of the case, the family of missing cruise ship honeymooner George Smith vows to fight for answers."48 Hours" correspondent Richard Schlesinger reports.

Charlie Kirk shooting suspect held without bail; Comedian Riki Lindhome opens up about her life and career.

American Amanda Knox followed her dream when she moved to Perugia, Italy, to study abroad and learn Italian. But that dream turned into a nightmare just weeks after her arrival when her roommate was found murdered.

Charlie Kirk shooting suspect’s family says he recently became more politically active; Why a leading breast cancer surgeon sings to her patients

Devastated after the FBI bows out of the case, the family of missing cruise ship honeymooner George Smith vows to fight for answers.

Romania's defense ministry said Saturday that the country's airspace had been breached by a drone during a Russian attack on infrastructure in neighboring Ukraine.

Conservative activist Charlie Kirk was shot and killed on Wednesday while speaking an event at Utah Valley University.

A White House official confirmed the extra funds would be directed to the U.S. Marshals Service and would also include enhanced protection for Supreme Court justices.

California lawmakers voted to phase out a group of chemicals known as PFAS, which are often called "forever chemicals​," in cookware.

Thousands of demonstrators packed London streets Saturday for a march organized by far-right activist Tommy Robinson.

President Trump said that NATO's commitment to winning the war in Ukraine "has been far less than 100%."

Leading breast cancer surgeon, Dr. Laura Esserman, goes beyond expectations to make the operating room more comfortable for her patients. Elizabeth Cook has the story.

Pope Leo XIV turned 70 years old on Saturday. Before becoming pontiff, he spent over two decades as a missionary and bishop in Peru. Lilia Luciano reports from Chiclayo, Peru.

Protests broke out in Chicago on Saturday against President Trump's immigration crackdown. A group of Catholic clergy led what they called a "People's Mass" outside the Great Lakes Naval Base. The base will also be used by Immigration and Customs Enforcement as a staging area for deportations. Camilo Montoya-Galvez spent a day with ICE agents in Chicago.

More than 100,000 people took to the streets in London on Saturday, in what's believed to be the largest anti-immigration protest in British history. Organizers called it a "Unite the Kingdom" rally. Haley Ott has more.

President Trump signaled a new position on Russia's war with Ukraine. He said the U.S. will agree to additional sanctions on Moscow, but only when NATO allies stop buying Russian oil. Willie James Inman has more details.

Tyler Robinson, the 22-year-old suspect in the murder of conservative activist Charlie Kirk, is being held in Spanish Fork, Utah. Officials have yet to identify a precise motive for Wednesday's shooting. Carter Evans has new developments.

What a major downward revision in U.S. jobs means for the economy; Reporter's Notebook: The end of the Great Resignation?

Earlier this month, the U.S. deported a group of non-Ghanaian nationals to Ghana, including deportees from Gambia and Nigeria.

Venezuela's foreign ministry said nine fishermen were "illegally and hostilely" detained on Friday by the USS Jason Dunham.

A Florida school is working hard to make sure all of its graduates have a way to go to college. Located in a county where only 17% of the population has a college education, all of the students in Roberts Junior Senior High School's graduating class are college-bound.

The White House confirmed that President Donald Trump had dinner with Qatar's Prime Minister Sheikh Mohammed bin Abdulrahman Al Thani in New York on Friday. The prime minister also met with the vice president and the Secretary of State. The meetings follow Israel's attack on Qatar's capital. The attack targeted Hamas leaders, Israel said.

The man accused of killing conservative commentator and activist Charlie Kirk is being held without bail in a Utah jail. Meanwhile, vigils and memorials across the country honored Kirk as his widow made her first public remarks since his death.

President Trump is escalating his use of the National Guard to crack down on crime in major cities. He appeared to shelve plans to send troops to Chicago, but said he will send them to Memphis instead.

An ICE agent shot and killed a man in Franklin Park, Illinois Friday morning after authorities say he attempted to drive into agents as they tried to make an arrest.

A U.S. Secret Service agent who wrote a negative social media post about Charlie Kirk has been put on leave, U.S. officials said Friday.

Advisory committee meetings help FDA scientists make decisions and increase public understanding of drug regulation, and abandoning them doesn't make sense, former officials said.

Meat from shark species at risk of extinction is commonly available in the U.S. under ambiguous or incorrect labels, researchers found.